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Tiny motors controlled in human cell
For the first time, scientists have placed tiny motors inside live human cells and steered them magnetically.
For the first time, scientists have placed tiny motors inside live human cells and steered them magnetically.
Molecular Biology
Source: BBC News
Posted on: Tuesday, Feb 11, 2014, 10:31am
Rating: | Views: 1103 | Comments: 0
Source: BBC News
Posted on: Tuesday, Feb 11, 2014, 10:31am
Rating: | Views: 1103 | Comments: 0
Scientists move closer to stem cell cure for type 1 diabetes
Researchers say they have reversed equivalent of type 1 diabetes in mice using stem cell transplants
Researchers say they have reversed equivalent of type 1 diabetes in mice using stem cell transplants
Molecular Biology
Source: TheGuardian
Posted on: Friday, Feb 07, 2014, 9:09am
Rating: | Views: 1152 | Comments: 0
Source: TheGuardian
Posted on: Friday, Feb 07, 2014, 9:09am
Rating: | Views: 1152 | Comments: 0
Ultra-Sharp Images of Cells, Made Using Fluorescent DNA
DNA can do many things -- build organisms, implicate criminals, store Shakespearean sonnets. Now, it can illuminate the complex biomolecular architecture of a cell. By attaching colored, fluorescent tags to short stretches of DNA, a team at Harvard University has ...
DNA can do many things -- build organisms, implicate criminals, store Shakespearean sonnets. Now, it can illuminate the complex biomolecular architecture of a cell. By attaching colored, fluorescent tags to short stretches of DNA, a team at Harvard University has ...
Molecular Biology
Source: Wired
Posted on: Wednesday, Feb 05, 2014, 8:17am
Rating: | Views: 1101 | Comments: 0
Source: Wired
Posted on: Wednesday, Feb 05, 2014, 8:17am
Rating: | Views: 1101 | Comments: 0
HIV infection causes immune cells to self-destruct, study says
Scientists say they have discovered a key process by which the AIDS virus kills key immune cells: It triggers a preprogrammed self-destruct sequence within the cell that is intended to alert fellow immune cells of a crisis.
Scientists say they have discovered a key process by which the AIDS virus kills key immune cells: It triggers a preprogrammed self-destruct sequence within the cell that is intended to alert fellow immune cells of a crisis.
Molecular Biology
Source: L.A. Times
Posted on: Friday, Dec 20, 2013, 10:42am
Rating: | Views: 1203 | Comments: 0
Source: L.A. Times
Posted on: Friday, Dec 20, 2013, 10:42am
Rating: | Views: 1203 | Comments: 0
Lasers Could Help Identify Malaria and Other Diseases Early
Technique reveals cell shape, enabling early diagnosis
Technique reveals cell shape, enabling early diagnosis
Molecular Biology
Source: Science
Posted on: Wednesday, Jul 03, 2013, 8:07am
Rating: | Views: 1138 | Comments: 0
Source: Science
Posted on: Wednesday, Jul 03, 2013, 8:07am
Rating: | Views: 1138 | Comments: 0
Scientists discover how rapamycin slows cell growth 
University of Montreal researchers have discovered a novel molecular mechanism that can potentially slow the progression of some cancers and other diseases of abnormal growth. In the May 23 edition of the prestigious journal Cell, scientists from the University of Montreal explain how they found that the anti-cancer and anti-proliferative drug rapamycin slows down or prevents cells from dividing.
University of Montreal researchers have discovered a novel molecular mechanism that can potentially slow the progression of some cancers and other diseases of abnormal growth. In the May 23 edition of the prestigious journal Cell, scientists from the University of Montreal explain how they found that the anti-cancer and anti-proliferative drug rapamycin slows down or prevents cells from dividing.
Molecular Biology
Source: University of Montreal
Posted on: Friday, May 24, 2013, 1:30pm
Rating: | Views: 4614 | Comments: 0
Source: University of Montreal
Posted on: Friday, May 24, 2013, 1:30pm
Rating: | Views: 4614 | Comments: 0
White tiger mystery solved
White tigers today are only seen in zoos, but they belong in nature, say researchers reporting new evidence about what makes those tigers white. Their spectacular white coats are produced by a single change in a known pigment gene, according to the study, appearing on May 23 in Current Biology, a Cell Press publication.
White tigers today are only seen in zoos, but they belong in nature, say researchers reporting new evidence about what makes those tigers white. Their spectacular white coats are produced by a single change in a known pigment gene, according to the study, appearing on May 23 in Current Biology, a Cell Press publication.
Genetics
Source: Cell Press
Posted on: Friday, May 24, 2013, 10:45am
Rating: | Views: 4063 | Comments: 0
Source: Cell Press
Posted on: Friday, May 24, 2013, 10:45am
Rating: | Views: 4063 | Comments: 0
Single-cell transfection tool enables added control for biological studies
Northwestern University researchers have developed a new method for delivering molecules into single, targeted cells through temporary holes in the cell surface. The technique could find applications in drug delivery, cell therapy, and related biological fields.
Northwestern University researchers have developed a new method for delivering molecules into single, targeted cells through temporary holes in the cell surface. The technique could find applications in drug delivery, cell therapy, and related biological fields.
Molecular Biology
Source: Northwestern University
Posted on: Wednesday, May 22, 2013, 11:45am
Rating: | Views: 2007 | Comments: 0
Source: Northwestern University
Posted on: Wednesday, May 22, 2013, 11:45am
Rating: | Views: 2007 | Comments: 0
Fast and painless way to better mental arithmetic? Yes, there might actually be a way
In the future, if you want to improve your ability to manipulate numbers in your head, you might just plug yourself in. So say researchers who report in the Cell Press journal Current Biology on May 16 on studies of a harmless form of brain stimulation applied to an area known to be important for math ability.
In the future, if you want to improve your ability to manipulate numbers in your head, you might just plug yourself in. So say researchers who report in the Cell Press journal Current Biology on May 16 on studies of a harmless form of brain stimulation applied to an area known to be important for math ability.
Neuroscience
Source: Cell Press
Posted on: Friday, May 17, 2013, 11:15am
Rating: | Views: 1761 | Comments: 0
Source: Cell Press
Posted on: Friday, May 17, 2013, 11:15am
Rating: | Views: 1761 | Comments: 0
Out of sync with the world: Body clocks of depressed people are altered at cell level
Every cell in our bodies runs on a 24-hour clock, tuned to the night-day, light-dark cycles that have ruled us since the dawn of humanity. The brain acts as timekeeper, keeping the cellular clock in sync with the outside world so that it can govern our appetites, sleep, moods and much more.
Every cell in our bodies runs on a 24-hour clock, tuned to the night-day, light-dark cycles that have ruled us since the dawn of humanity. The brain acts as timekeeper, keeping the cellular clock in sync with the outside world so that it can govern our appetites, sleep, moods and much more.
Molecular Biology
Source: University of Michigan Health System
Posted on: Tuesday, May 14, 2013, 8:30am
Rating: | Views: 2357 | Comments: 0
Source: University of Michigan Health System
Posted on: Tuesday, May 14, 2013, 8:30am
Rating: | Views: 2357 | Comments: 0
MicroRNA cooperation mutes breast cancer oncogenes
A University of Colorado Cancer Center study recently published in the journal Cell Death & Disease shows that turning up a few microRNAs a little may offer as much anti-breast-cancer activity as turning up one microRNA a lot – and without the unwanted side effects.
A University of Colorado Cancer Center study recently published in the journal Cell Death & Disease shows that turning up a few microRNAs a little may offer as much anti-breast-cancer activity as turning up one microRNA a lot – and without the unwanted side effects.
Molecular Biology
Source: University of Colorado Denver
Posted on: Wednesday, May 08, 2013, 12:15pm
Rating: | Views: 2260 | Comments: 0
Source: University of Colorado Denver
Posted on: Wednesday, May 08, 2013, 12:15pm
Rating: | Views: 2260 | Comments: 0
New insights into Ebola infection pave the way for much-needed therapies
The Ebola virus is among the deadliest viruses on the planet, killing up to 90% of those infected, and there are no approved vaccines or effective therapies. A study published by Cell Press on May 7th in the Biophysical Journal reveals how the most abundant protein making up the Ebola virus—viral protein 40 (VP40)—allows the virus to leave host cells and spread infection to other cells thro
The Ebola virus is among the deadliest viruses on the planet, killing up to 90% of those infected, and there are no approved vaccines or effective therapies. A study published by Cell Press on May 7th in the Biophysical Journal reveals how the most abundant protein making up the Ebola virus—viral protein 40 (VP40)—allows the virus to leave host cells and spread infection to other cells thro
Molecular Biology
Source: Cell Press
Posted on: Wednesday, May 08, 2013, 10:00am
Rating: | Views: 6275 | Comments: 0
Source: Cell Press
Posted on: Wednesday, May 08, 2013, 10:00am
Rating: | Views: 6275 | Comments: 0
Activity of cancer inducing genes can be controlled by the cell's skeleton
Cancer is a complex disease, in which cells undergo a series of alterations, including changes in their architecture; an increase in their ability to divide, to survive and to invade new tissues or metastasis. A category of genes, called oncogenes, is critical during cancer progression, as they codify proteins whose activity favours the development of cancer. One of these molecules, Src, is implic
Cancer is a complex disease, in which cells undergo a series of alterations, including changes in their architecture; an increase in their ability to divide, to survive and to invade new tissues or metastasis. A category of genes, called oncogenes, is critical during cancer progression, as they codify proteins whose activity favours the development of cancer. One of these molecules, Src, is implic
Molecular Biology
Source: Instituto Gulbenkian de Ciencia
Posted on: Tuesday, May 07, 2013, 4:15pm
Rating: | Views: 2053 | Comments: 0
Source: Instituto Gulbenkian de Ciencia
Posted on: Tuesday, May 07, 2013, 4:15pm
Rating: | Views: 2053 | Comments: 0
Wip1 could be new target for cancer treatment
Researchers have uncovered mutations in the phosphatase Wip1 that enable cancer cells to foil the tumor suppressor p53, according to a study in The Journal of Cell Biology. The results could provide a new target for the treatment of certain cancers.
Researchers have uncovered mutations in the phosphatase Wip1 that enable cancer cells to foil the tumor suppressor p53, according to a study in The Journal of Cell Biology. The results could provide a new target for the treatment of certain cancers.
Cancer
Source: Rockefeller University Press
Posted on: Tuesday, May 07, 2013, 12:45pm
Rating: | Views: 1534 | Comments: 0
Source: Rockefeller University Press
Posted on: Tuesday, May 07, 2013, 12:45pm
Rating: | Views: 1534 | Comments: 0
Scientists create personalized bone substitutes from skin cells
A team of New York Stem Cell Foundation (NYSCF) Research Institute scientists report today the generation of patient-specific bone substitutes from skin cells for repair of large bone defects. The study, led by Darja Marolt, PhD, a NYSCF-Helmsley Investigator and Giuseppe Maria de Peppo, PhD, a NYSCF Research Fellow, and published in the Proceedings of the National
A team of New York Stem Cell Foundation (NYSCF) Research Institute scientists report today the generation of patient-specific bone substitutes from skin cells for repair of large bone defects. The study, led by Darja Marolt, PhD, a NYSCF-Helmsley Investigator and Giuseppe Maria de Peppo, PhD, a NYSCF Research Fellow, and published in the Proceedings of the National
Molecular Biology
Source: New York Stem Cell Foundation
Posted on: Tuesday, May 07, 2013, 11:15am
Rating: | Views: 1609 | Comments: 0
Source: New York Stem Cell Foundation
Posted on: Tuesday, May 07, 2013, 11:15am
Rating: | Views: 1609 | Comments: 0
Video: Computer simulations reveal the energy landscape of ion channels
Every cell of our body is separated from its environment by a lipid bilayer. In order to maintain their biological function and to transduce signals, special proteins, so called ion channels, are embedded in the membrane.
Every cell of our body is separated from its environment by a lipid bilayer. In order to maintain their biological function and to transduce signals, special proteins, so called ion channels, are embedded in the membrane.
Molecular Biology
Source: University of Vienna
Posted on: Monday, May 06, 2013, 10:15am
Rating: | Views: 2012 | Comments: 0
Source: University of Vienna
Posted on: Monday, May 06, 2013, 10:15am
Rating: | Views: 2012 | Comments: 0
Kids with brains that under-react to painful images
When children with conduct problems see images of others in pain, key parts of their brains don't react in the way they do in most people. This pattern of reduced brain activity upon witnessing pain may serve as a neurobiological risk factor for later adult psychopathy, say researchers who report their findings in the Cell Press journal Current Biology on May 2.
When children with conduct problems see images of others in pain, key parts of their brains don't react in the way they do in most people. This pattern of reduced brain activity upon witnessing pain may serve as a neurobiological risk factor for later adult psychopathy, say researchers who report their findings in the Cell Press journal Current Biology on May 2.
Neuroscience
Source: Cell Press
Posted on: Friday, May 03, 2013, 10:30am
Rating: | Views: 1372 | Comments: 0
Source: Cell Press
Posted on: Friday, May 03, 2013, 10:30am
Rating: | Views: 1372 | Comments: 0
It slices, it dices, it silences: ADAR1 as gene-silencing modular RNA multitool
RNA, once considered a bit player in the grand scheme by which genes encode protein, is increasingly seen to have a major role in human genetics. In a study presented in the April 25 issue of the journal Cell, researchers from The Wistar Institute discovered how the RNA-editing protein, ADAR1, also combines with the protein called Dicer to create microRNA (miRNA) and small interfering (siRN
RNA, once considered a bit player in the grand scheme by which genes encode protein, is increasingly seen to have a major role in human genetics. In a study presented in the April 25 issue of the journal Cell, researchers from The Wistar Institute discovered how the RNA-editing protein, ADAR1, also combines with the protein called Dicer to create microRNA (miRNA) and small interfering (siRN
Molecular Biology
Source: The Wistar Institute
Posted on: Thursday, May 02, 2013, 4:00pm
Rating: | Views: 5943 | Comments: 0
Source: The Wistar Institute
Posted on: Thursday, May 02, 2013, 4:00pm
Rating: | Views: 5943 | Comments: 0
Membrane remodeling: Where yoga meets cell biology
Cells ingest proteins and engulf bacteria by a gymnastic, shape-shifting process called endocytosis. Researchers at the National Institutes of Health revealed how a key protein, dynamin, drives the action.
Cells ingest proteins and engulf bacteria by a gymnastic, shape-shifting process called endocytosis. Researchers at the National Institutes of Health revealed how a key protein, dynamin, drives the action.
Molecular Biology
Source: NIH/National Institute of General Medical Sciences
Posted on: Wednesday, May 01, 2013, 2:15pm
Rating: | Views: 1660 | Comments: 0
Source: NIH/National Institute of General Medical Sciences
Posted on: Wednesday, May 01, 2013, 2:15pm
Rating: | Views: 1660 | Comments: 0
As people live longer and reproduce less, natural selection keeps up
In many places around the world, people are living longer and are having fewer children. But that's not all. A study of people living in rural Gambia, published in the Cell Press journal Current Biology on April 25, shows that this modern-day "demographic transition" may lead women to be taller and slimmer, too.
In many places around the world, people are living longer and are having fewer children. But that's not all. A study of people living in rural Gambia, published in the Cell Press journal Current Biology on April 25, shows that this modern-day "demographic transition" may lead women to be taller and slimmer, too.
Health
Source: Cell Press
Posted on: Friday, Apr 26, 2013, 11:00am
Rating: | Views: 1645 | Comments: 0
Source: Cell Press
Posted on: Friday, Apr 26, 2013, 11:00am
Rating: | Views: 1645 | Comments: 0
Link between inherited endocrine tumor syndrome and much-studied cell pathway
A mutation in a protein called menin causes a hereditary cancer syndrome called MEN1 (multiple endocrine neoplasia type 1). Individuals with MEN1 are at a substantially increased risk of developing neuroendocrine tumors, including cancer of the pancreatic islet cells that secrete insulin.
A mutation in a protein called menin causes a hereditary cancer syndrome called MEN1 (multiple endocrine neoplasia type 1). Individuals with MEN1 are at a substantially increased risk of developing neuroendocrine tumors, including cancer of the pancreatic islet cells that secrete insulin.
Molecular Biology
Source: University of Pennsylvania School of Medicine
Posted on: Thursday, Apr 25, 2013, 1:30pm
Rating: | Views: 1519 | Comments: 0
Source: University of Pennsylvania School of Medicine
Posted on: Thursday, Apr 25, 2013, 1:30pm
Rating: | Views: 1519 | Comments: 0
New light shed on early stage Alzheimer's disease
The disrupted metabolism of sugar, fat and calcium is part of the process that causes the death of neurons in Alzheimer's disease. Researchers from Karolinska Institutet in Sweden have now shown, for the first time, how important parts of the nerve cell that are involved in the cell's energy metabolism operate in the early stages of the disease. These somewhat surprising results shed new light on
The disrupted metabolism of sugar, fat and calcium is part of the process that causes the death of neurons in Alzheimer's disease. Researchers from Karolinska Institutet in Sweden have now shown, for the first time, how important parts of the nerve cell that are involved in the cell's energy metabolism operate in the early stages of the disease. These somewhat surprising results shed new light on
Molecular Biology
Source: Karolinska Institutet
Posted on: Tuesday, Apr 23, 2013, 11:00am
Rating: | Views: 1839 | Comments: 0
Source: Karolinska Institutet
Posted on: Tuesday, Apr 23, 2013, 11:00am
Rating: | Views: 1839 | Comments: 0
A check on tension
Ludwig researchers Arshad Desai and Christopher Campbell, a post-doctoral fellow in his laboratory, were conducting an experiment to parse the molecular details of cell division about three years ago, when they engineered a mutant yeast cell as a control that, in theory, had no chance of surviving. Apparently unaware of this, the mutant thrived.
Ludwig researchers Arshad Desai and Christopher Campbell, a post-doctoral fellow in his laboratory, were conducting an experiment to parse the molecular details of cell division about three years ago, when they engineered a mutant yeast cell as a control that, in theory, had no chance of surviving. Apparently unaware of this, the mutant thrived.
Molecular Biology
Source: Ludwig Institute for Cancer Research
Posted on: Monday, Apr 22, 2013, 2:45pm
Rating: | Views: 1482 | Comments: 0
Source: Ludwig Institute for Cancer Research
Posted on: Monday, Apr 22, 2013, 2:45pm
Rating: | Views: 1482 | Comments: 0
Same protein that fires up cancer-promoting Erk also blocks its activation
A protein which is intimately involved in cancer-promoting cell signaling also keeps a key component of the signaling pathway tied down and inactive, a team led by scientists from The University of Texas MD Anderson Cancer Center reports this week in Nature Structural Molecular Biology.
A protein which is intimately involved in cancer-promoting cell signaling also keeps a key component of the signaling pathway tied down and inactive, a team led by scientists from The University of Texas MD Anderson Cancer Center reports this week in Nature Structural Molecular Biology.
Molecular Biology
Source: University of Texas M. D. Anderson Cancer Center
Posted on: Monday, Apr 22, 2013, 1:15pm
Rating: | Views: 1408 | Comments: 0
Source: University of Texas M. D. Anderson Cancer Center
Posted on: Monday, Apr 22, 2013, 1:15pm
Rating: | Views: 1408 | Comments: 0
Researchers discover that stem cell senescence drives aging
Declining levels of the protein BubR1 occur when both people and animals age, and contribute to cell senescence or deterioration, weight loss, muscle wasting and cataracts. Mayo Clinic researchers have shown that adult progenitor or stem cells -- important for repair and regeneration of skeletal muscle and maintenance of healthy fat tissue -- are subject to cellular senescence,
Declining levels of the protein BubR1 occur when both people and animals age, and contribute to cell senescence or deterioration, weight loss, muscle wasting and cataracts. Mayo Clinic researchers have shown that adult progenitor or stem cells -- important for repair and regeneration of skeletal muscle and maintenance of healthy fat tissue -- are subject to cellular senescence,
Molecular Biology
Source: Mayo Clinic
Posted on: Friday, Apr 19, 2013, 12:00pm
Rating: | Views: 3633 | Comments: 0
Source: Mayo Clinic
Posted on: Friday, Apr 19, 2013, 12:00pm
Rating: | Views: 3633 | Comments: 0
Learned helplessness in flies and the roots of depression
When faced with impossible circumstances beyond their control, animals, including humans, often hunker down as they develop sleep or eating disorders, ulcers, and other physical manifestations of depression. Now, researchers reporting in the Cell Press journal Current Biology on April 18 show that the same kind of thing happens to flies.
When faced with impossible circumstances beyond their control, animals, including humans, often hunker down as they develop sleep or eating disorders, ulcers, and other physical manifestations of depression. Now, researchers reporting in the Cell Press journal Current Biology on April 18 show that the same kind of thing happens to flies.
Neuroscience
Source: Cell Press
Posted on: Friday, Apr 19, 2013, 11:45am
Rating: | Views: 1642 | Comments: 0
Source: Cell Press
Posted on: Friday, Apr 19, 2013, 11:45am
Rating: | Views: 1642 | Comments: 0
New stem cell-based screen reveals promising drug for Lou Gehrig's disease
Amyotrophic lateral sclerosis (ALS), also called Lou Gehrig's disease, is a fatal disease that causes motor neurons, which are responsible for controlling muscles, to die. A study published by Cell Press on April 18th in Cell Stem Cell has revealed a novel stem-cell-based approach to screen for effective treatments, which are sorely lacking. Applying this method to motor neurons derived fro
Amyotrophic lateral sclerosis (ALS), also called Lou Gehrig's disease, is a fatal disease that causes motor neurons, which are responsible for controlling muscles, to die. A study published by Cell Press on April 18th in Cell Stem Cell has revealed a novel stem-cell-based approach to screen for effective treatments, which are sorely lacking. Applying this method to motor neurons derived fro
Molecular Biology
Source: Cell Press
Posted on: Friday, Apr 19, 2013, 11:30am
Rating: | Views: 1461 | Comments: 0
Source: Cell Press
Posted on: Friday, Apr 19, 2013, 11:30am
Rating: | Views: 1461 | Comments: 0
Cancer cell metabolism kills
ATP is the main energy currency of cells and one might expect that not only contracting muscle, but also uncontrollably dividing cancer cells would have a high demand for ATP. However, for some reason cancer cells have re-programmed their metabolic engines to produce less ATP. The phenomenon, known as Warburg effect, is typical for cancer cells and the mechanism behind is believed to benefit cance
ATP is the main energy currency of cells and one might expect that not only contracting muscle, but also uncontrollably dividing cancer cells would have a high demand for ATP. However, for some reason cancer cells have re-programmed their metabolic engines to produce less ATP. The phenomenon, known as Warburg effect, is typical for cancer cells and the mechanism behind is believed to benefit cance
Molecular Biology
Source: University of Helsinki
Posted on: Tuesday, Apr 16, 2013, 11:00am
Rating: | Views: 1670 | Comments: 0
Source: University of Helsinki
Posted on: Tuesday, Apr 16, 2013, 11:00am
Rating: | Views: 1670 | Comments: 0
Cell-destroyer that fights and promotes TB reveals what's behind its split identity
Tumor necrosis factor – normally an infection-fighting substance produced by the body– can actually heighten susceptibility to tuberculosis if its levels are too high.
Tumor necrosis factor – normally an infection-fighting substance produced by the body– can actually heighten susceptibility to tuberculosis if its levels are too high.
Molecular Biology
Source: University of Washington
Posted on: Friday, Apr 12, 2013, 1:15pm
Rating: | Views: 1477 | Comments: 0
Source: University of Washington
Posted on: Friday, Apr 12, 2013, 1:15pm
Rating: | Views: 1477 | Comments: 0
Genetic master controls expose cancers' Achilles' heel
In a surprising finding that helps explain fundamental behaviors of normal and diseased cells, Whitehead Institute scientists have discovered a set of powerful gene regulators dubbed "super-enhancers" that control cell state and identity. Healthy cells employ these super-enhancers to control genes responsible for cellular functions and developmental transitions—
In a surprising finding that helps explain fundamental behaviors of normal and diseased cells, Whitehead Institute scientists have discovered a set of powerful gene regulators dubbed "super-enhancers" that control cell state and identity. Healthy cells employ these super-enhancers to control genes responsible for cellular functions and developmental transitions—
Molecular Biology
Source: Whitehead Institute for Biomedical Research
Posted on: Friday, Apr 12, 2013, 12:45pm
Rating: | Views: 1461 | Comments: 0
Source: Whitehead Institute for Biomedical Research
Posted on: Friday, Apr 12, 2013, 12:45pm
Rating: | Views: 1461 | Comments: 0
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